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SAB News

SAB Members in the News
Posted 4/8/2002

Joseph M. Miano, Ph.D., Member since February 2002
Dr. Miano was invited as the sole U.S. scientist to a retinoid symposium in Heidelberg, Germany this past March.  The symposium brought together many of the world's experts on retinoids to discuss possible therapeutic uses of retinoids for vascular and renal diseases.

His lab also just published a paper on the use of bacterial artificial chromosomes to begin delineating the transcriptional control of the human smooth muscle calponin gene. The paper will appear in the May issue of the American Journal of Physiology, Heart and Circulatory Physiology.

Juan Miranda-Rios, Ph.D., Member since June 1999
Dr. Miranda-Rios published a seminal paper in PNAS USA last year, “A Conserved RNA structure (thi box) Is Involved in Regulation of Thiamin Biosynthetic Gene Expression in Bacteria,” which was mentioned on the journal’s cover.  Dr. G. Stormo provided the commentary, “Do mRNA Act as Direct Sensors of Small Molecules to Control Their Expression?”
Citation: Proceedings of the National Academy of Sciences USA, Vol. 98, Issue 17, 9736-9741, August 14, 2001.

Dana Perkins, Ph.D., Member since March 2001
Dr. Perkins and her fellow lab members recently published in the Journal of Virology a paper on the anti-apoptotic activity of the Herpes Simplex Virus Type 2 gene, ICP10 PK.  This paper describes a novel discovery because ICP10 PK is the only known viral gene that activates a survival pathway in hippocampal neurons.
Citation:  Perkins D, Pereira EFR, Gober M, Yarowsky PJ, Aurelian L The herpes simple xvirus type 2 R1 protein kinase (ICP10 PK) blocks apoptosis in hippocampal neurons, involving activation of the MEK/MAPK survival pathway. Journal of Virology. 2002 Feb; 76(3): 1435-49.

Maurizio Popoli, Ph.D., Member since October 2001
Dr. Popoli has received a 2001 Independent Investigator Award from NARSAD, (National Alliance for Research on Schizophrenia and Depression, Great Neck, NY). His research project "Structural and molecular synaptic changes induced by antidepressants," was funded from September 2001 to September 2003.

William Thurman, Member since February 2002
Mr. Thurman has patents on the following devices: an oxygenator, a cardiometer reservoir, blood filters used in open heart surgery, dialysis catheters and a spirometer for measuring lung function.

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m.scott@scienceboard.net

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