Preclinical KRAS inhibitor triggers complete responses in pancreatic tumors
A small molecule KRASG12D inhibitor has triggered complete responses in preclinical pancreatic cancer models, raising hopes that the approach can improve outcomes in the hard-to-treat tumor type. Read More
Cryo-EM reveals 3D structure of inflammasomes implicated in multiple diseases
Using cryo-electron microscopy (cryo-EM), researchers from Harvard Medical School and Peking University have generated 3D images of the inflammasome in its active state for the first time, enabling scientists to view a structure linked to multiple diseases in near-atomic resolution. Read More
Multivalent mRNA vaccine protects animals against variety of influenza strains
A multivalent mRNA vaccine has protected animals against a variety of influenza strains, suggesting the candidate could play a role in mitigating the threat of seasonal and pandemic flu. Read More
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