Machine learning used to encode commands for immune cells December 9, 2022 -- Researchers at University of California San Francisco (UCSF), in collaboration with a team at IBM Research, have developed a virtual molecular library of thousands of “command sentences” for cells, based on combinations of “words” that guide engineered immune cells to seek out and kill cancer cells without pausing.Read More
Salk Institute scientists identify oncogene activation December 8, 2022 -- Researchers at the Salk Institute have zeroed in on the mechanisms that activate oncogenes, showing that genetic mutation activity depends on the distance between a particular gene and the sequences that regulate the gene.Read More
New method helps scientists identify efficient, tailored AI algorithms December 6, 2022 -- Researchers from Cold Spring Harbor Laboratory have developed a new method designed to assist scientists in choosing artificial intelligence (AI) algorithms that best fit their needs. Their findings may help researchers in identifying more efficient AI programs to analyze the human genome.Read More
Transcriptomics help visualize diffuse midline glioma December 6, 2022 -- A Dana-Farber-led team used spatial single-cell transcriptomics to visualize diffuse midline glioma cancer cell structure across different age groups and locations. Their study, published December 5 in the journal Nature Genetics, provides insights that may facilitate new treatment approaches for this rare cancer.Read More
Researchers pinpoint gene leading to childhood glaucoma December 5, 2022 -- A genetic mutation in the thrombospondin-1 gene leads to the development of severe childhood glaucoma and the discovery may improve disease screening and personalize treatments, a team of scientists has found.Read More
CRISPR-based tool cuts and pastes genes where needed November 28, 2022 -- Massachusetts Institute of Technology researchers have designed a new CRISPR-based tool that can snip out faulty DNA sequences and safely replace them with new ones at desired cell sites.Read More