Cancer & Disease Research
New antibody-based immunotherapy for prostate cancer
Researchers in a study have found the monoclonal antibody enoblituzumab to be safe and effective in men with aggressive prostate cancer. Read More
Dialing down activity of Cas enzyme improves safety of CRISPR gene editing in mice
Scientists have modified the synthetic guide RNA (gRNA) that enables CRISPR-Cas gene editing to make the process safer for use in humans. Read More
Study claims surface transmission ‘contributes significantly’ to the spread of COVID-19
Researchers have generated what they say is “the first empirical evidence” that the presence of SARS-CoV-2 on people’s hands and surfaces “contributes significantly to the spread of COVID-19.” Read More
Insights into how viruses assemble in cells unlock opportunities to improve gene therapy
Researchers have revealed how viral nucleic acids are packaged into particles in cells, generating insights that could improve the delivery of gene therapies and treatment of infectious diseases. Read More
Research reveals possible gene therapies for polycystic kidney disease
Researchers have found that a small piece of a specific protein might be key to preventing autosomal dominant polycystic kidney disease. Their study, published March 30 in Nature Communications, could lead to new gene therapies for treating the disease, the researcher said. Read More
English study finds demographic differences in COVID-19 rates between pandemic waves
An observational study in England found major ethnic, religious, and social differences in the risk of testing positive for SARS-CoV-2 between the second and third waves of the pandemic. Read More
Wyss Institute, Boston Children’s Hospital, Northpond Labs to develop next-gen platform for compound screening
The Wyss Institute for Biologically Inspired Engineering at Harvard University said on Tuesday that it has entered into an agreement with Boston Children’s Hospital and Northpond Labs involving the development of an in vitro high-throughput platform that can identify compounds that bind target proteins with relevance to diseases. Read More
Monoclonal antibodies reduced COVID-19 hospitalization, death risk by a third: Study
During the COVID-19 pandemic, healthcare providers nationwide administered an evolving array of monoclonal antibody treatments, previously untested on such a large scale. A study, published Monday in the Annals of Internal Medicine, showed that this effort saved lives. Read More
Live nasal COVID-19 vaccine candidate beats intramuscular mRNA shot in hamsters
A nasally delivered, live-attenuated vaccine against COVID-19 has outperformed an intramuscular mRNA shot in hamsters, encouraging researchers to prepare to study the candidate in humans. Read More
RNA biomarkers may help confirm heart disease, study finds
An analysis of blood RNA from patients with angiographically confirmed coronary artery disease has shown how RNA biomarkers may be used to confirm heart disease. Read More
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