Genomics
Gene overexpression may protect against Alzheimer’s disease: study
Scientists at the University of Colorado Anschutz Medical Campus have discovered the overexpression of a gene tied to cell division and the structure and function of neurons may prevent and protect against cognitive decline in both mice and humans with Alzheimer’s disease. Read More
Induced pluripotent stem cell technology offers potential treatment for hair loss
Science Advisory Board spoke with Stemson Therapeutics co-founder and CEO Geoff Hamilton earlier this month at the 2022 Cell & Gene Meeting on the Mesa about the preclinical stage cell therapy company's focus on curing hair loss by leveraging the regenerative power of induced pluripotent stem cells. Read More
Procedure finds large deletions, other anomalies in 'on-target' CRISPR-Cas9 editing
Single-molecule real-time sequencing has enabled Rice University researchers to find and quantify unintended genetic changes that can occur when CRISPR-Cas9 makes on-target DNA cuts. Read More
Cell therapy startup NKILT Therapeutics takes novel approach to targeting leukemia
Biotech startup NKILT Therapeutics is developing a novel approach of engineering natural killer cells to directly target leukemias and solid tumors. Science Advisory Board spoke with Raphaël Ognar, co-founder and CEO of the company earlier this month at the 2022 Cell & Gene Meeting on the Mesa in Carlsbad, CA. Read More
Identification of genetic drivers of radiotherapy sensitivity opens door to treatment optimization
Using in silico and experimental profiling platforms, researchers at Northwestern Medicine have identified genetic biomarkers of radiation sensitivity, pointing to opportunities to use genomics to guide radiotherapy treatment for cancer patients. Read More
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